Intra-tympanic delivery of short interfering RNA into the adult mouse cochlea
نویسندگان
چکیده
منابع مشابه
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The discovery of RNA interference (RNAi) in mammalian cells has created a new class of therapeutics based on the reversible silencing of specific disease-causing genes. This therapeutic potential depends on the ability to deliver inducers of RNAi, such as short-interfering RNA (siRNA) and micro-RNA (miRNA), to cells of target tissues. This chapter reviews various challenges and delivery strateg...
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ژورنال
عنوان ژورنال: Hearing Research
سال: 2013
ISSN: 0378-5955
DOI: 10.1016/j.heares.2012.10.011